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Phosphorylation Activation

Molecular classification: Post-translational modification, Regulatory mechanism

Overview

Phosphorylation activation refers to the process by which the addition of a phosphate group (phosphorylation) to specific amino acid residues in proteins—most commonly serine, threonine, or tyrosine—leads to a functional change in the target protein. This mechanism is central to cellular signaling and regulation, especially for protein kinases, which are enzymes that catalyze phosphorylation events.

Biological functions

Signal transductionRegulation of cell cycleRegulation of growthRegulation of apoptosisRegulation of metabolism

Disease associations

CancerImmune disorders

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