Physical removal of malignant tissue

“Physical removal of malignant tissue” refers to surgical interventions designed to treat cancer by excising (cutting out) malignant growths and, often, a margin of healthy tissue around them to minimize the risk of recurrence. This encompasses various procedures—including excision, tumor resection, Mohs surgery, and wide local excision—for many cancer types. The main goal is to achieve complete tumor removal, often followed by analysis of the margins to confirm no residual disease. Physical removal is generally not a drug target, receptor, enzyme, or transporter but rather a primary mode of cancer therapy. This approach is effective for tumors that are localized and accessible; in more advanced cases, surgery may be part of combination therapy, also involving chemotherapy, radiation, or immunotherapy. The appropriateness and risks of surgery depend on tumor location, stage, patient health, and other factors[2][3][4][6][7][8][9].

Other names

Surgical excisiontumor resectioncancer surgeryMohs surgerywide local excisiontumor removal