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Physical root canal sealing is a clinical procedure and treatment outcome in endodontics, not a molecular target, receptor, enzyme, or any other type of therapeutic target. It involves the process of filling and obturating root canals with materials such as gutta-percha and sealers to prevent bacterial reinfection and microleakage. It describes a mechanical and chemical sealing action rather than a biological molecule or macromolecule that could be targeted by drugs.
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