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Physical wound coverage refers to the use of materials—such as bandages, dressings, films, or scaffolds—to physically protect wound sites against external contaminants, mechanical trauma, and dehydration, while often providing an optimal environment for tissue repair and regeneration. Physical wound coverage is a core technique in wound management, enabling natural wound healing phases such as hemostasis, inflammation, proliferation, and remodeling to occur under safer or more controlled conditions[1][2][3][4]. These coverings do not act as molecular targets but can be medicated, promote granulation and epithelialization, or serve as scaffolds for cellular migration and tissue regeneration.
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