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Physiological function

01

Overview

The term 'Physiological function' refers to the normal activities and processes of living organisms and their parts, rather than a specific molecular target such as a protein, enzyme, or receptor [1]. In the context of drug discovery and pharmacology, a target must be a discrete biological entity—typically a macromolecule—that interacts with a drug to produce a therapeutic effect [2]. Because 'Physiological function' is a broad categorical description of biological activity, it cannot be classified as a therapeutic target, nor can it be mapped to specific molecular classifications, interacting drugs, or disease roles [1][2]. To provide meaningful data for biotech analysis, a specific biological molecule (e.g., a specific receptor, ion channel, or kinase) must be identified [2]. [1] National Cancer Institute. (n.d.). NCI Dictionary of Cancer Terms: Target. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/target [2] Overington, J. P., Al-Lazikani, B., & Hopkins, A. L. (2006). How many drug targets are there? Nature Reviews Drug Discovery. https://doi.org/10.1038/nrd2199

02

Mechanism of action

Not applicable as this is a general biological concept, not a discrete molecular target.

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