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"Physiological metabolic pathways" refers to the complex, interconnected sequences of enzyme-catalyzed biochemical reactions that convert substrates into energy and essential cellular components, enabling homeostasis, growth, and adaptation. These include both anabolic pathways (which build up molecules using energy) and catabolic pathways (which break down molecules to release energy), and are central to all living systems. The term encompasses a wide range of cellular processes, each mediated by distinct enzymes and regulatory mechanisms, and cannot be considered a single therapeutic target[1][3][5][9].
Not applicable at the pathway collection level; for individual enzymes or pathway components: inhibition, activation, or modulation of enzymatic activity, signaling, or substrate transport[4][6].
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