Physiological nutritional pathways

Physiological nutritional pathways encompass the complex network of biochemical processes and signaling cascades responsible for the ingestion, absorption, metabolism, and utilization of nutrients within an organism (StatPearls, 2023). These pathways include macronutrient metabolism (carbohydrates, lipids, and proteins) and micronutrient utilization, regulated by key sensors such as the mechanistic target of rapamycin (mTOR) and adenosine monophosphate-activated protein kinase (AMPK) (PubMed, 2021). While these pathways are fundamental to maintaining energy homeostasis and cellular function, the term refers to a broad physiological framework rather than a single, discrete therapeutic target. Dysregulation of these pathways is central to the pathogenesis of metabolic diseases like obesity, type 2 diabetes, and cardiovascular disorders (NIH, 2022). Pharmacological interventions typically target specific enzymes, transporters, or receptors within these pathways to modulate metabolic health rather than the entire system as a whole.

Other names

Metabolic pathwaysNutrient sensing pathwaysNutritional metabolismEnergy homeostasis pathways

Not applicable as this is a broad physiological concept rather than a specific molecular target.