PLAC8 like 1 (PLAC8L1)

PLAC8 like 1 (PLAC8L1) is a protein-coding gene that encodes a member of the PLAC8 motif-containing protein family, characterized by a conserved cysteine-rich domain (CCXXXXCPC or CLXXXXCPC region)[4][5]. It is expressed in blood cells and vascular endothelium in model organisms such as zebrafish, and is orthologous to the human gene PLAC8L1[4]. Unlike PLAC8 (placenta-specific 8, onzin), which has been studied for roles in tumor progression and cell proliferation, there are currently no published functional data, molecular mechanism, or association with disease or therapeutic targeting for PLAC8L1 in humans. Information about biological function, disease relevance, or pharmacological targeting is lacking, and there is no evidence that PLAC8L1 is considered a receptor, enzyme, transporter, or validated therapeutic target in the biomedical literature[4][5]. Key points and limitations: - The query likely confuses PLAC8L1 with PLAC8, the latter of which has established roles in cancer biology and cellular regulation[1][2], whereas PLAC8L1 currently lacks such evidence. - PLAC8L1 is not recognized as a standard target in therapeutics, has no known ligands or drugs, and its biological function and disease associations remain uncharacterized[4][5]. Note: Given the near-absence of detailed information, PLAC8L1 should not be considered a therapeutic target at this time, and the entry is marked is_incorrect: true as there is insufficient evidence to support it as a druggable or disease-associated molecular target.

Other names

PLAC8-like protein 1PLAC8L1