Target intelligence / Profile preview

Plant Genomic DNA (gDNA)

Target
gDNA
Molecular classification
Nucleic acid, Deoxyribonucleic acid, Other
01

Overview

Plant genomic DNA represents the complete set of genetic instructions required for the growth, development, and reproduction of plants, distributed across the nucleus, chloroplasts, and mitochondria (NCBI, 2023). It serves as the primary template for RNA synthesis and subsequent protein production, making it the master regulator of plant physiology and biochemistry. In biotechnology and agriculture, plant genomic DNA is the substrate for genetic modification and genome editing, aimed at enhancing crop resilience and nutritional content (Nature Reviews Genetics, 2019). While it is not a traditional therapeutic target for human diseases, it is frequently manipulated using chemical mutagens like ethyl methanesulfonate or biological tools like CRISPR-Cas9 to study gene function or develop new plant varieties. Understanding the complexity and organization of plant genomes is essential for addressing global challenges such as food security and climate change adaptation.

Other names
Plant genomeBotanical DNAVegetable DNANuclear DNAChloroplast DNAMitochondrial DNA
02

Mechanism of action

DNA alkylation, DNA intercalation, DNA strand cleavage, and site-specific gene editing.

03

Biological functions

Genetic information storageInheritanceTranscriptionReplicationOther
04

Disease associations

InfectionOther
05

Safety considerations

Off-target mutationsHorizontal gene transferEnvironmental impact of transgenesBiodiversity loss
06

Interacting drugs

Ethyl methanesulfonate (EMS)

4 more in the full profile.

07

Biomarkers

Single nucleotide polymorphisms (SNPs)Simple sequence repeats (SSRs)DNA methylation patterns

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