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"Plant macronutrient uptake pathways" encompasses the **integrated network of transporters, channels, co-transporters, carriers, and sensors** that plants use to acquire essential macronutrients for growth, metabolism, and survival. These include, but are not limited to: - **Nitrate transporters (NRT1, NRT2)**, **ammonium transporters (AMTs)**, and other specialized transporters for nitrogen[3]. - **Potassium channels/carriers** (e.g., AKT1, AtHAK5)[6], **phosphate transporters (PHT1)**, **sulfate transporters (SULTR1, SULTR2)**, and **calcium/magnesium uptake systems**[1][5][6]. - Many of these are regulated at both the transcriptional and post-translational level, with plant roots able to upregulate high-affinity systems under nutrient-deficient conditions[1][3][5]. - Additional control occurs via root-to-shoot signaling, interaction with soil microbiota (such as mycorrhizal fungi), and feedback from nutrient status[2][5][6]. Because this entry refers to a **class of molecular transport processes and regulatory mechanisms rather than a discrete target**, it is not suitable for use as a therapeutic target entity in a structured drug discovery context. Any structured information should be assigned to the specific transporter or sensor proteins involved in these pathways—such as "High-affinity nitrate transporter 2.1 (NRT2.1)" or "Phosphate transporter 1;1 (PHT1;1)"—rather than to this pathway-level collective. If you seek structured information about individual nutrient transporters or regulators, please specify the relevant molecule or gene.
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