Plasma exudation

Plasma exudation refers to the process by which plasma, the liquid component of blood containing proteins and other solutes, moves from post-capillary venules into surrounding tissues or onto mucosal surfaces in response to inflammatory stimuli. This is not a simple exaggeration of normal capillary exchange but a specific inflammatory reaction involving increased vascular permeability. The process allows immune components such as proteins and cells to access sites of injury or infection for defense and repair without necessarily causing tissue damage or edema. Plasma exudation is observed in both health and disease states—such as during airway inflammation—where it can serve protective roles but may also contribute to pathological features if excessive[1][2]. Note that "plasma exudation" describes a physiological/pathophysiological process rather than a discrete molecular target like a receptor, enzyme, transporter, or ion channel. It does not have an associated gene/protein product nor is it directly targeted by drugs; instead, therapies may aim at modulating the underlying mechanisms (e.g., reducing vascular permeability) involved in this process[1][2].

Other names

ExudatePlasma extravasationInflammatory exudate