Plasma proteins other than immunoglobulins (None commonly used; plasma proteins may be collectively abbreviated as "PPs," but not standardized specifically for non-immunoglobulin plasma proteins.)

Plasma proteins other than immunoglobulins are a diverse group of soluble proteins present in blood plasma, responsible for vital physiological functions including transport of substances, maintenance of oncotic pressure, blood coagulation, immune defense, inflammation regulation, and tissue repair. This group comprises albumin, acute phase proteins, coagulation factors, complement proteins, transporters, protease inhibitors, oncofetal proteins, and other soluble shed proteins. Most are synthesized in the liver (with some exceptions), and their broad involvement in disease and medical therapy underscores their importance as both diagnostic biomarkers and therapeutic targets in hematology, immunology, cardiovascular, oncologic, hepatic, and genetic conditions. The category is not a specific molecular target but a collective term for multiple clinically important plasma soluble proteins.

Other names

Plasma non-immunoglobulin proteinsNon-Ig plasma proteinsPlasma structural and functional proteins (excluding immunoglobulins)

Replacement therapy: restoring deficient plasma proteins Inhibition of protein activity: e.g., direct inhibition of complement, clotting cascade Modulation of inflammatory response: dampening acute-phase protein synthesis, cytokine signaling Protein binding: transport/drug displacement effects Immune modulation