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Target intelligence / Profile preview
Plasma Volume (PV)
- Target
- PV
- Molecular classification
- Body Fluid, Physiological Parameter
01
Overview
Plasma volume refers to the total volume of blood plasma present in the circulatory system. Blood plasma is the pale yellow, liquid component of blood in which blood cells are suspended. Plasma is primarily composed of water, but also contains dissolved proteins, glucose, clotting factors, electrolytes, hormones, carbon dioxide, and oxygen. It plays a critical role in maintaining osmotic balance and transporting substances throughout the body. Alterations in plasma volume can indicate or contribute to various medical conditions.
02
Biological functions
Transport of nutrients, waste products, hormonesMaintenance of osmotic balanceTransport of proteinsExtracellular fluid compartment
03
Disease associations
DehydrationShockLiver diseaseVitamin C deficiencyAddison's diseaseHeart failureChronic hypertensionKidney failure
04
Safety considerations
Changes in plasma volume can affect drug concentrations and efficacy.Extreme changes in plasma volume can be life-threatening.
05
Biomarkers
Plasma volume is itself a biomarker for hydration status and certain diseases.
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