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Target intelligence / Profile preview
Platelet-derived growth factor receptor-like 2, pseudogene (PDGFRL2P)
- Target
- PDGFRL2P
- Molecular classification
- Other (pseudogene)
01
Overview
Platelet-derived growth factor receptor-like 2, pseudogene (PDGFRL2P) is classified as a pseudogene related to the platelet-derived growth factor receptor family. Pseudogenes such as PDGFRL2P arise from gene duplication or retrotransposition but contain inactivating mutations or truncations that typically prevent transcription into functional proteins. PDGFRL2P does not code for an active protein, is not a receptor, and is not considered a therapeutic or pharmacological target. If a biologically relevant gene or active PDGF family receptor was intended, the proper targets would be "Platelet-derived growth factor receptor alpha (PDGFRA)" or "Platelet-derived growth factor receptor beta (PDGFRB)", both of which are functional receptor tyrosine kinases involved in cell proliferation, development, and disease, including cancer and fibrosis[1][2][3][4]. There is no established therapeutic, diagnostic, or safety information specific to PDGFRL2P.
- Other names
- PDGFRL2Pplatelet-derived growth factor receptor like 2, pseudogene
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