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PLBD1 antisense RNA 1 (PLBD1-AS1)
- Target
- PLBD1-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Non-coding RNA, Antisense RNA
01
Overview
PLBD1 antisense RNA 1 (PLBD1-AS1) is a long non-coding RNA (lncRNA) gene located on chromosome 12, transcribed antisense to the PLBD1 protein-coding gene[1][3][4][9]. It does not encode a protein. While the exact function of PLBD1-AS1 is unknown, current research suggests it may play a role in regulating gene expression, potentially by affecting the stability or translation of PLBD1 messenger RNA, but specific molecular mechanisms and biological significance remain uncharacterized[3][9]. PLBD1-AS1 is not a therapeutic target such as a receptor, enzyme, or transporter, and there are no known interacting drugs, mechanisms of drug action, or biomarker associations at this time[3][4][9]. There is a correlative disease association with meconium ileus, but no direct evidence for a pathogenic or functional role in disease[4].
- Other names
- PLBD1-AS1
02
Biological functions
Regulation of gene expression (putative)
03
Disease associations
Meconium ileus (reported disease association based on correlative studies)
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