Target intelligence / Profile preview

PLD5 pseudogene 1 (PLD5P1)

Target
PLD5P1
Molecular classification
Other (Pseudogene)
01

Overview

PLD5P1 (PLD5 pseudogene 1) is a processed pseudogene related to the *PLD5* gene (phospholipase D family member 5), located in the human genome[4]. Pseudogenes are DNA sequences similar to functional genes but typically do not encode functional proteins due to mutations, insertions, deletions, or regulatory changes that prevent normal gene expression or protein function[4]. While some pseudogenes have regulatory roles, PLD5P1 has no recognized protein-coding ability, no known biological or pathological function, and is not considered a therapeutic target.\n\nKey clarifications:\n- PLD5P1 is a pseudogene, not an enzyme, receptor, transporter, or transcription factor.\n- There is no current evidence of clinical or biological relevance, therapeutic targeting, or pathophysiological association for PLD5P1 specifically.\n- It should *not* be confused with PLD5, which is a protein-coding gene, although the function of PLD5 itself is also not well characterized in the context of pharmacology or therapeutics.\n\nSummary:\nPLD5 pseudogene 1 (PLD5P1) is a non-coding pseudogene lacking established function, disease association, or relevance as a therapeutic target[4]. If this entry was proposed as a therapeutic target, this is incorrect.

Other names
phospholipase D family member 5 pseudogene 1
02

Mechanism of action

None

03

Biological functions

None established; pseudogenes can sometimes regulate gene expression (e.g., as regulatory RNAs), but no such function is described for PLD5P1 specifically[4].
04

Disease associations

None established for PLD5P1; in general, pseudogenes can sometimes be implicated in cancer or other diseases by acting as competitive endogenous RNAs, but no disease role is known for PLD5P1[2][4].
05

Safety considerations

None
06

Interacting drugs

None
07

Biomarkers

None

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