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Pleckstrin homology domain containing, family B (evectins) member 2 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

This genomic locus encodes a pseudogene, similar in sequence to the canonical human protein-coding gene "pleckstrin homology domain containing, family B (evectins) member 2" (PLEKHB2). Pseudogenes such as this do not produce functional proteins and are typically considered genomic relics without protein-coding activity or known biological function. Consequently, this entity is not considered a therapeutic target or receptor, and is not implicated in disease, drug interaction, or clinical biomarker panels. The functional version (PLEKHB2, ENSG00000115762) encodes a protein involved in endosomal transport, but ENSG00000231198 lacks such activity[2][5].

Other names
LOC100422519pleckstrin homology domain containing, family B member 2 pseudogenePLEKHB2 pseudogene

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