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Pleiomorphic adenoma gene-like 2 pseudogene (ENSG00000214980, LOC152845) is a processed or unprocessed pseudogene in the human genome, showing sequence similarity to the functional gene pleiomorphic adenoma gene-like 2 (PLAGL2) but containing disabling mutations that prevent it from encoding a functional protein[2][5][6]. Like other pseudogenes, it is regarded as a non-protein-coding element and is not considered a therapeutic target. While some pseudogenes may participate in gene regulation or disease by acting at the DNA, RNA, or even protein level through rare mechanisms, there is no evidence for a functional role for this specific pseudogene. It should not be confused with the functional gene pleiomorphic adenoma gene-like 2 (PLAGL2), which is a zinc finger transcription factor involved in development and several cancers, but is a distinct locus[1][3][5].
None. No known drug mechanism involves this pseudogene.
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