PLEKHM2 antisense RNA 1 (PLEKHM2-AS1)

PLEKHM2 antisense RNA 1 (PLEKHM2-AS1) is a long non-coding RNA gene located antisense to the protein-coding gene PLEKHM2. As an antisense lncRNA, it may play a role in the post-transcriptional or epigenetic regulation of the PLEKHM2 gene, analogous to other antisense lncRNAs that modulate gene stability, expression, or chromatin state[2]. However, there is currently no direct experimental evidence describing its biological function, its disease relevance, or its candidacy as a therapeutically actionable target. The molecule is distinguished from canonical drug targets by its non-protein coding nature and lack of direct disease associations. Thus, PLEKHM2-AS1 is best classified as a genomic regulatory RNA with largely uncharacterized function and no current pharmacological targeting or biomarker status[4][6].

Other names

PLEKHM2-AS1PLEKHM2 antisense RNA 1