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Plenum Osshp synthetic biphasic bone scaffold (null)
- Target
- null
- Molecular classification
- Other (synthetic biphasic bioceramic; bone substitute material), Null for classical protein/gene/receptor/enzyme families
01
Overview
Plenum Osshp is a **synthetic biphasic bone substitute** composed of hydroxyapatite (HA, 70%) and β-tricalcium phosphate (β-TCP, 30%), engineered to be highly porous with ceramic particles optimized for osteoconductivity. It serves as a physical scaffold for bone regeneration, mimicking the structure of trabecular bone and facilitating homogeneous new bone formation. Its design allows for the adsorption of fluids and nutrients, and its synthetic nature ensures no risk of disease transmission from animal or human sources. Plenum Osshp is mainly used in dental surgery and implantology for guided bone regeneration in areas with critical bone defects, and has shown comparable efficacy to other commercial synthetic bone substitutes[1][3].
- Other names
- Plenum OsshpPlenum® OsshpPlenum Oss hpPlenum Oss~hp
02
Mechanism of action
null
03
Biological functions
Osteoconduction (acts as a scaffold for bone-forming cells)Bone repairBone regeneration
04
Disease associations
Repair of bone defectsPeriodontal lesion recoveryDental implant supportGuided bone regeneration
05
Safety considerations
Reported as safe with predictable bone regeneration, absence of animal/human origin components, and excellent biocompatibility[1][3].General safety concerns may include risk for infection, incomplete bone integration, or biomaterial retention, but no specific major safety flags noted in published studies.
06
Biomarkers
Possibly used with markers of bone formation such as osteocalcin, osteopontin, RUNX2, vascular endothelial growth factor, and Integrin Binding Sialoprotein during research[3].No specific patient selection biomarkers.
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