Pleural adhesion

Pleural adhesion describes the formation of fibrous connective tissue bands between the parietal and visceral pleural surfaces, typically following inflammation, infection (such as tuberculous pleurisy or malignancy), trauma, or surgical intervention. Clinically, they are detected radiologically or intraoperatively and can restrict lung movement, contribute to persistent pneumothorax, and complicate thoracic surgery. They are a pathological outcome, not a discrete molecular or cellular therapeutic target and do not correspond to a canonical molecule, protein, receptor, or gene. Pleural adhesion should not be treated as a druggable target or molecular entity; instead, it is a structural result of disease or intervention and is associated with clinical management challenges rather than molecular biology.

Other names

Pleural adhesionspleural fibrous bands

Not applicable. Drugs like sclerosing agents induce local inflammation and fibrosis to create pleural adhesions as a therapeutic intervention.