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Pleural Mesothelial Cells (PMCs)
- Target
- PMCs
- Molecular classification
- Epithelial Cells
01
Overview
Pleural mesothelial cells (PMCs) are specialized cells that form the monolayer lining of the pleura. They maintain homeostasis within the pleural space by providing a protective barrier, regulating fluid volume, acting as immune sentinels, and participating in tissue repair. Dysregulation can contribute to diseases like pleural mesothelioma, pleuritis, and effusions.
- Other names
- Mesothelial CellsPleural Lining Cells
02
Biological functions
Barrier protectionLubricationImmune surveillanceTissue repairFluid regulationAntigen presentationPhagocytosis
03
Disease associations
Pleural MesotheliomaPleuritisPleural EffusionIdiopathic Pulmonary Fibrosis (IPF)
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