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Plum Allergen
- Molecular classification
- Allergen, Non-specific Lipid Transfer Protein (nsLTP), Profilin, Thaumatin-like protein, PR-10 protein
01
Overview
Plum allergen refers to the proteins in plums (*Prunus domestica*) that can trigger allergic reactions in sensitized individuals. Major allergens include Pru d 3 (a non-specific Lipid Transfer Protein), profilin, thaumatin-like protein, and PR-10 proteins. Allergic reactions range from oral allergy syndrome to anaphylaxis. Cross-reactivity with other *Prunus* species and latex is common. Diagnosis involves skin prick tests and serum-specific IgE measurement.
- Other names
- Prunus domestica allergenPru d 3 (nsLTP)Plum profilinPlum thaumatin-like proteinPlum PR-10 protein
02
Biological functions
Plant defenseLipid binding/transfer (nsLTP)Actin binding (Profilin)Unknown (Thaumatin-like protein)Defense against pathogens (PR-10)
03
Disease associations
Food allergyOral Allergy Syndrome (OAS)Anaphylaxis
04
Safety considerations
Cross-reactivity with other Prunus species (apricot, cherry, peach)Cross-reactivity with latex allergensVariable allergenicity depending on geographic region (LTP vs. Profilin sensitization)Potential for severe allergic reactions, including anaphylaxis
05
Biomarkers
Serum-specific IgE against Prunus domestica
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