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PMS1 homolog 2, mismatch repair system component pseudogene 1 (PMS2P1) is a pseudogene located on chromosome 7, similar to the functional PMS2 mismatch repair gene. As a pseudogene, PMS2P1 does not encode a functional protein but shares high sequence homology with PMS2. Its presence can complicate genetic testing of PMS2 due to potential gene conversion or mispriming. PMS2P1 itself does not participate in DNA mismatch repair, disease etiology, or serve as a therapeutic target or biomarker in human disease.
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