PNRC1 divergent transcript (PNRC1-DT)

PNRC1 divergent transcript (PNRC1-DT) is a long non-coding RNA (lncRNA) gene located at the PNRC1 locus, distinct from the protein-coding PNRC1 gene[4][6]. Unlike PNRC1, which encodes a nuclear receptor coactivator implicated in tumor suppression and rRNA processing regulation[1][3][6], PNRC1-DT is an RNA molecule believed to arise from divergent transcription at the locus and does not encode a functional protein. Its biological function, disease roles, and therapeutic relevance remain undetermined. There is frequent confusion between PNRC1-DT (the non-coding transcript) and PNRC1 (the nuclear receptor coactivator protein), but they are scientifically and functionally distinct. If you require information about the protein-coding PNRC1, which acts as a nuclear receptor coactivator and has emerging roles in cancer biology, please clarify, as that is a true molecular target with established literature[1][3][6]. For PNRC1-DT, data is limited and it is not considered a drug target.

Other names

PNRC1 Divergent TranscriptPNRC1-DT