Target intelligence / Profile preview

Poliovirus

Molecular classification: Virus, Enterovirus, Picornaviridae

Overview

Poliovirus is a small, nonenveloped virus that causes poliomyelitis. It enters cells by binding to the CD155 receptor. While not a therapeutic target itself, understanding its mechanism of infection is crucial for developing antiviral strategies and vaccines.

Biological functions

Viral replicationInfectionCell entry

Disease associations

Poliomyelitis (Polio)ParalysisRespiratory failure

Safety considerations

Potential for paralysisRespiratory failurePost-polio syndrome

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