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Target intelligence / Profile preview
Poliovirus Type 1/2/3 Antigen (Poliovirus 1/2/3 Antigen)
- Target
- Poliovirus 1/2/3 Antigen
- Molecular classification
- Viral protein, Capsid protein, Antigen
01
Overview
The poliovirus type 1/2/3 antigen refers to the structural proteins (antigens) present on the surface of the three serotypes of poliovirus: type 1, type 2, and type 3. These antigens are primarily responsible for eliciting an immune response and are critical components in both inactivated (IPV) and oral (OPV) polio vaccines. They are not therapeutic targets in themselves, but rather components used to elicit an immune response.
- Other names
- Poliovirus capsid proteinPV1 antigenPV2 antigenPV3 antigenPoliovirus structural proteins
02
Mechanism of action
N/A
03
Biological functions
Eliciting immune responseViral entryAntigen presentation
04
Disease associations
PoliomyelitisAcute flaccid paralysisVaccine development
05
Safety considerations
Vaccine-derived poliovirus (VDPV) circulationPotential for reversion to virulence in OPV
06
Interacting drugs
Formaldehyde
2 more in the full profile.
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