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Target intelligence / Profile preview
Inactivated poliovirus antigen type 3 (IPV-3)
- Target
- IPV-3
- Molecular classification
- Viral antigen, Capsid protein, Protein complex
01
Overview
- Other names
- Poliovirus Type 3 antigenInactivated Poliovirus Vaccine Type 3Saukett strain antigenPoliovirus type 3 (Saukett) inactivated antigen
02
Mechanism of action
The antigen induces a humoral immune response by presenting viral epitopes to the host immune system, specifically stimulating B lymphocytes to produce neutralizing IgG antibodies. These antibodies circulate systemically and neutralize wild-type Poliovirus Type 3 upon exposure, preventing viral entry into host cells and subsequent replication in the central nervous system (StatPearls, 2023; FDA, 2022).
03
Biological functions
Immune response inductionAntibody productionAcquired immunity
04
Disease associations
PoliomyelitisInfection
05
Safety considerations
Injection site erythemaInjection site painFeverHypersensitivity}
06
Interacting drugs
Inactivated Poliovirus Vaccine (IPOL)
4 more in the full profile.
07
Biomarkers
Anti-poliovirus type 3 neutralizing antibody titerSeroconversion rate
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