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Target intelligence / Profile preview
Poliovirus types 1, 2, and 3 (inactivated) (IPV)
- Target
- IPV
- Molecular classification
- Virus, Picornaviridae, Enterovirus, Enterovirus C
01
Overview
Poliovirus types 1, 2, and 3 (inactivated) refers to the inactivated forms of the three poliovirus serotypes used in the Inactivated Poliovirus Vaccine (IPV). These inactivated viruses are non-infectious but retain their antigenic properties, allowing them to stimulate an immune response and protect against poliomyelitis. IPV induces systemic immunity by stimulating neutralizing antibodies.
- Other names
- Inactivated Poliovirus VaccineIPVPoliovirus types 1, 2, and 3PV-1, PV-2, PV-3 (inactivated)Salk vaccine
02
Mechanism of action
Stimulates the production of neutralizing antibodies against poliovirus serotypes 1, 2, and 3, providing protection against paralytic polio.
03
Biological functions
AntigenImmunogenInduction of neutralizing antibodiesPrevention of poliomyelitis
04
Disease associations
Prevention of Poliomyelitis
05
Safety considerations
Rare allergic reactionsNo risk of vaccine-derived polio paralysis (VDPV) as the virus is inactivated
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