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Target intelligence / Profile preview
POLR2M pseudogene 1 (POLR2MP1)
- Target
- POLR2MP1
- Molecular classification
- Pseudogene
01
Overview
POLR2MP1 is a pseudogene derived from the POLR2M locus encoding RNA polymerase II subunit M. Pseudogenes such as POLR2MP1 are typically non-functional DNA sequences resembling protein-coding genes but lacking the ability to produce intact functional proteins. No evidence exists for direct biological function, role in disease, or druggability. The alternative name "GLURR2" is not supported in authoritative resources and appears to be a misassignment (possibly intended for "GluR2", a glutamate receptor subunit unrelated to the RNA polymerase family). As a pseudogene, POLR2MP1 is not a therapeutic target and does not have molecular functions, interacting drugs, or clinical utility.
- Other names
- POLR2M pseudogene 1POLR2MP1
02
Mechanism of action
None. No drugs are known to act on POLR2MP1.
03
Biological functions
None for the pseudogene. Pseudogenes typically do not perform biological functions unless shown to regulate gene expression through non-coding RNA activity, which is not supported for POLR2MP1.
04
Disease associations
None for the pseudogene. The protein-coding ancestor gene POLR2M is associated with childhood infratentorial ependymoma and familial spinal neurofibromatosis. There are no established disease associations or roles for POLR2MP1.
05
Safety considerations
None reported. Since it is not a protein-coding gene or drug target, therapeutic safety concerns do not apply.
06
Interacting drugs
None known.
07
Biomarkers
None established.
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