Polymerase (DNA) delta 1, catalytic subunit pseudogene (LOC100422453)

The target "polymerase, delta 1, catalytic subunit 125kDa pseudogene" (ENSG00000217483; LOC100422453) is annotated as a **pseudogene** of the protein-coding gene POLD1, which encodes DNA polymerase delta 1, the 125kDa catalytic subunit essential for DNA replication and repair[1][2][4]. Unlike the functional POLD1 gene, which is involved in lagging strand DNA synthesis, proofreading, and DNA damage repair, the pseudogene does not produce a protein and has no known biological function, disease association, or drug targeting relevance. Structured drug discovery, biomarker application, and therapeutic intervention all apply to the protein-coding gene POLD1, not its pseudogene LOC100422453. If you seek information on a bona fide drug target, refer to **polymerase (DNA) delta 1, catalytic subunit (POLD1)**, not its pseudogene (ENSG00000217483 / LOC100422453)[1][2][3][4].

Other names

polymerase (DNA) delta 1, catalytic subunit pseudogeneLOC100422453pseudogene of POLD1

None. Pseudogene does not encode any protein, so there is no mechanism of action.