POM121 and zona pellucida glycoprotein 3 fusion pseudogene fragment (POMZP3)

POMZP3 is a human gene fragment that resulted from the fusion of DNA sequences originating from two different loci: two internal exons of the POM121 gene (which encodes an integral nuclear pore membrane protein) and four 3' exons from the ZP3 gene (which encodes a zona pellucida glycoprotein important in oocyte biology). The resulting pseudogene fragment does not encode a functional, native protein, as the predicted product lacks key localization and function motifs of its parent genes. The transcripts (and any translated products) are not implicated in disease biology, protein function, or therapeutic targeting, and do not have established roles as receptors, enzymes, or other canonical targets. This pseudogene is detected in several human tissues at the mRNA level, but there is no evidence for relevant biological or clinical function. This entry describes a pseudogene fragment rather than a canonical therapeutic target. There is no recognized biological function, disease association, clinical interest, or drug interaction. Any reference to protein isoforms or recombinant fusion proteins (e.g., in commercial protein catalogues) relates to research use only, not to physiological or pathophysiological function. This target should not be considered further in therapeutic target or drug discovery pipelines. If you need to identify or validate actual therapeutic targets related to POM121 or ZP3 (e.g., zona pellucida glycoprotein 3, which is involved in fertilization), those should be addressed as separate, canonical entries.

Other names

POM-ZP3POM121 and ZP3 fusionPOMZP3 pseudogenePOM121 and ZP3 fusion proteinPOZP3_HUMAN