POM121 transmembrane nucleoporin C pseudogene

The *POM121 transmembrane nucleoporin C pseudogene* is a genomic locus similar to the POM121 family of genes, which produce transmembrane nucleoporin proteins essential for the assembly and function of the nuclear pore complex (NPC)[2][5][7]. However, by definition as a pseudogene, ENSG00000271071 is not protein-coding and is not considered a valid therapeutic target, classically understood as a receptor, enzyme, transporter, or transcription factor. Pseudogenes often arise following gene duplication or mutation and can be markers of evolutionary processes but typically do not exhibit biological activity or direct involvement in disease; however, their functional relatives (such as *POM121*, *POM121C*) are essential nuclear pore complex components, affecting cell cycle, nucleocytoplasmic transport, and associated with cancer and metabolic disease[1][2][3]. The presence of "pseudogene" in this locus name and lack of evidence in the search results for any encoded protein or drug interaction means it is not a valid target[5][7]. Note: If you intended a protein-coding nucleoporin, refer to *POM121* or *POM121C*, not the pseudogene. If you require information about the protein-coding gene *POM121C*, see the corresponding entries (ENSG00000272391)[2].

Other names

POM121 membrane glycoprotein B (pseudogene)POM121L1P