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Target intelligence / Profile preview
POM121 transmembrane nucleoporin-like 2 pseudogene (POM121L2P)
- Target
- POM121L2P
- Molecular classification
- Other (pseudogene; not protein-coding), Related to nucleoporin family
01
Overview
The POM121 transmembrane nucleoporin-like 2 pseudogene (ENSG00000277227) is a non-protein-coding genomic sequence related to the POM121 family of nucleoporin genes, which encode transmembrane constituents of the nuclear pore complex essential for nucleocytoplasmic transport. The pseudogene is highly homologous to protein-coding family members but does not encode a functional product, is not known to have any direct biological function, and is not a drug target. Protein-coding paralogs such as POM121L2 are structural components of the nuclear pore complex, potentially involved in RNA export and protein import into nucleus, but such functions do not apply to the pseudogene.
- Other names
- POM121L2 pseudogenePOM121 transmembrane nucleoporin-like 2 pseudogeneENSG00000277227
02
Biological functions
None (as a pseudogene, it does not have known biological functions)Functional roles described only for the protein-coding paralog POM121L2, which is involved in nuclear pore structure, RNA export, protein import into nucleus
03
Disease associations
Other (no direct disease association for the pseudogene)Disease associations and roles in nuclear transport are described for the protein-coding gene and family members (POM121)
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