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Porcine protein allergens are proteins derived from pigs (Sus scrofa) that can trigger allergic reactions in sensitized individuals. The most significant allergens identified in pork are Sus s 1 (porcine serum albumin) and the carbohydrate epitope alpha-gal (galactose-α-1,3-galactose). These proteins can cause a range of allergic responses, from mild skin symptoms to severe anaphylaxis. Management primarily involves strict avoidance of pork and products containing porcine-derived ingredients, along with emergency preparedness for anaphylactic reactions.
Epinephrine acts as an emergency treatment for anaphylaxis by reversing symptoms like bronchoconstriction and hypotension.
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