Postmeiotic segregation increased 2 pseudogene 5 (PMS2P5)

Postmeiotic segregation increased 2 pseudogene 5" (PMS2P5, ENSG00000304176) is a non-coding RNA or pseudogene that is antisense to SPDYE12. It is classified as a member of the PMS2 gene family, which is best known for its role in DNA mismatch repair via the canonical PMS2 protein. However, unlike PMS2, PMS2P5 is not known to produce a functional protein and has no established role in DNA repair or any other cellular process. Its annotation as a "novel transcript, antisense to SPDYE12" reflects its genomic location rather than functional significance. There is no evidence that this gene acts as a therapeutic target, nor is there any information linking it to direct drug interactions, disease associations, or functional protein activities[5][7]. Summary: ENSG00000304176 (PMS2P5) is a non-functional pseudogene with no established therapeutic, enzymatic, or receptor activity. It should not be considered a drug target. Its primary significance is as a genomic element related to the PMS2 and SPDYE12 gene regions[5][7].

Other names

PMS2L5PMS7postmeiotic segregation increased 2 pseudogene 5postmeiotic segregation increased 2-like 5PMS2P5ENSG00000304176