Target intelligence / Profile preview

POT1 antisense RNA 1 (POT1-AS1)

Target: POT1-AS1
Molecular classification: Other (long non-coding RNA)

Overview

POT1 antisense RNA 1 (POT1-AS1, LOC101928283) is a long non-coding RNA located near the POT1 gene, transcribed in the antisense direction. It does not encode a protein but is implicated in the regulation of gene expression at the RNA level. Recent studies suggest POT1-AS1 inhibits epithelial-mesenchymal transition (EMT), marking it as a potential regulator in cancer progression and metastasis, particularly in gastric carcinoma and possibly other cancers. However, its mechanistic details, druggability, and biomarker roles are not well elucidated in current literature[6]. It is not a receptor, enzyme, transporter, or conventional therapeutic target, and no interacting drugs or safety concerns specific to POT1-AS1 have been reported.

Other names: POT1-AS1LOC101928283

Biological functions

Potential regulator of gene expressionImplicated in modulation of epithelial-mesenchymal transition (EMT) in carcinomas

Disease associations

Cancer (evidence for a role in various carcinomas, including gastric cancer)

Beyond the preview

Go deeper on POT1 antisense RNA 1 (POT1-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on POT1 antisense RNA 1 (POT1-AS1).

Explore the full profile