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Target intelligence / Profile preview
Potassium bicarbonate (KHCO₃)
- Target
- KHCO₃
- Molecular classification
- Other
01
Overview
Potassium bicarbonate is an inorganic salt (KHCO₃), appearing as a white, odorless crystalline powder, highly soluble in water but insoluble in alcohol. It dissociates in solution to provide potassium ions and bicarbonate ions, and is used for electrolyte replenishment, as an antacid, fire extinguisher powder, agricultural fungicide, and leavening agent in baking powders. Medicinally, it aids in managing potassium deficiency and neutralizing gastric acid, but it is not a molecular target (such as a receptor, enzyme, or transporter), nor is it a signaling molecule or biomolecular entity.
- Other names
- Potassium hydrogencarbonatePotassium acid carbonateK-LyteKalicinite (mineral form)KaliumhydrogencarbonatKafyloxKHCO₃
02
Mechanism of action
Electrolyte repletion: Provides bioavailable potassium ion for physiological needs. Antacid: Neutralizes excess gastric acid (HCl + KHCO₃ → KCl + CO₂ + H₂O). Fungicidal: Disrupts fungal hyphal walls and shrinks conidia via bicarbonate action
03
Biological functions
Electrolyte supplementationAcid-base homeostasisSource of CO₂ for leaveningFungicide
04
Disease associations
Potassium deficiency/hypokalemiaAcid-base disturbances (mild metabolic acidosis)Fungal infection (agriculture)
05
Safety considerations
Risk of hyperkalemiaMetabolic alkalosisGI irritationCaution in patients with heart or kidney disease
06
Interacting drugs
Potassium-raising agents
2 more in the full profile.
07
Biomarkers
Serum potassium concentrationSerum bicarbonate and blood pH
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