Potassium Channel (K⁺ Channel)

Potassium channels are a diverse group of transmembrane proteins that selectively conduct potassium ions (K⁺) across cell membranes. They are essential for regulating membrane potential, shaping action potentials, and controlling various cellular processes, including hormone secretion and cell volume regulation. Malfunction of potassium channels can lead to various diseases such as arrhythmias, epilepsy, and diabetes. They are therapeutic targets for conditions like arrhythmias, hypertension, epilepsy, pain syndromes, autoimmune diseases, and cancer proliferation/migration control.

Other names

K ChannelPotassium-selective channel

Block or open the potassium channel pore, thereby modulating potassium ion flow across the cell membrane and altering membrane potential or cellular excitability.