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Target intelligence / Profile preview
Potassium Voltage-Gated Channel (Kv channel)
- Target
- Kv channel
- Molecular classification
- Ion channel, Voltage-gated ion channel
01
Overview
Potassium voltage-gated channels (Kv channels) are a family of transmembrane proteins that selectively conduct potassium ions (K⁺) across cell membranes in response to changes in membrane potential. They play a critical role in generating and propagating action potentials, regulating neuronal excitability, and maintaining resting membrane potential.
- Other names
- Voltage-gated potassium channelKv channels
02
Mechanism of action
Modulation of ion flow across the cell membrane via voltage-dependent gating
03
Biological functions
Regulation of membrane potentialAction potential generation and propagationNeuronal excitabilityImmune response modulation
04
Disease associations
Neurological disordersCardiac arrhythmiasAutoimmune diseasesCancer
05
Safety considerations
Potential for cardiac arrhythmiasNeurological side effectsImmune suppression
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