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Target intelligence / Profile preview
Potassium voltage-gated channel subfamily C member 1 and Potassium voltage-gated channel subfamily C member 2 (Kv3.1/Kv3.2)
- Target
- Kv3.1/Kv3.2
- Molecular classification
- Ion channel, Voltage-gated potassium channel, Shaw-type potassium channel
01
Overview
- Other names
- KCNC1KCNC2Shaw-related subfamily member 1Shaw-related subfamily member 2Voltage-gated potassium channel Kv3.1Voltage-gated potassium channel Kv3.2Shaw-like potassium channel
02
Biological functions
Action potential repolarization [1, 13]Fast-spiking neuronal firing [13, 20]Neurotransmitter release regulation [13, 15]Gamma oscillation generation [1, 10]Sensory processing [1, 13]Motor coordination [1, 21]
03
Disease associations
Schizophrenia [1, 10]Epilepsy [1, 17]Progressive myoclonic epilepsy [1, 17]Developmental and epileptic encephalopathy [1, 17]Hearing loss [1, 13]Tinnitus [10]Alzheimer's disease [1]Fragile X syndrome [13]Ataxia [1, 15]Cognitive impairment [2, 14]
04
Interacting drugs
AUT00063 [10]
7 more in the full profile.
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