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Target intelligence / Profile preview
Potassium Voltage-Gated Channel Subfamily KQT Member 3 (KCNQ3)
- Target
- KCNQ3
- Molecular classification
- Ion channel, Voltage-gated potassium channel, Potassium channel
01
Overview
KCNQ3 encodes a protein that forms part of the voltage-gated potassium channels in neurons, specifically the M-channel. These channels are crucial for regulating neuronal excitability by transporting potassium ions out of cells, which helps generate and transmit electrical signals in the nervous system. Mutations in KCNQ3 have been linked to benign familial neonatal seizures (BFNS).
- Other names
- Potassium channel subunit alpha KvLQT3Voltage-gated potassium channel subunit Kv7.3KQT-like 3BFNC2EBN2KV7.3
02
Mechanism of action
Not applicable; KCNQ3 is a target, not a drug
03
Biological functions
Regulation of neuronal excitabilityPotassium ion transportMembrane potential stabilization
04
Disease associations
EpilepsyBenign familial neonatal seizures (BFNS)
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