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Target intelligence / Profile preview
Potassium voltage-gated channel subfamily Q member 5 (KCNQ5)
- Target
- KCNQ5
- Molecular classification
- Ion channel, Voltage-gated potassium channel
01
Overview
KCNQ5 is a pore-forming subunit of the voltage-gated potassium (Kv) channel family. It plays a crucial role in regulating neuronal excitability by contributing to the M-current. It can form heteromeric channels with other members of its family, notably with KCNQ3. Mutations or dysfunctions in KCNQ family members are linked to neurological disorders.
- Other names
- Kv7.5KvLQT5KQT-like 5Potassium channel subunit alpha KvLQT5
02
Mechanism of action
Modulation of M-current, a slowly activating and deactivating potassium conductance.
03
Biological functions
Regulation of neuronal excitabilitySynaptic transmissionProtein complex assemblyPotassium ion transport
04
Disease associations
Neurological disorders
05
Interacting drugs
Barium
5 more in the full profile.
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