POTE ankyrin domain family member B3 (POTEB3)

POTE ankyrin domain family member B3 (POTEB3) is a human protein-coding gene belonging to the POTE ankyrin domain family, which is characterized by the presence of ankyrin repeats and shared sequence features across paralogs[2][9]. POTEB3 is primarily named for its expression in the prostate, ovary, and testis, and is located on chromosome 15[8]. Its precise biological functions remain unclear, but family members are generally thought to have roles in cellular scaffolding or protein-protein interactions[4]. POTEB3 has been associated in some genomic studies with childhood kidney cell carcinoma, though direct mechanistic or therapeutic significance is unestablished[2]. There are currently no known drugs, confirmed receptor activity, or widely recognized biomarker or safety concerns related to POTEB3, and it is not currently considered a classical therapeutic target such as a receptor, enzyme, or transporter[2][9].

Other names

POTE-15POTEBPOTE ankyrin domain family member BPOTE ankyrin domain family, member B3POTE ankyrin domain family, member B-likeANKRD26-like family B member 1Prostate, ovary, testis-expressed protein on chromosome 15