POTE ankyrin domain family member C pseudogene

ENSG00000289133 represents a pseudogene related to the POTE ankyrin domain family, member C. The POTE gene family consists of multiple paralogs that are primate-specific and are implicated in cancer biology and cytoskeletal interactions. The pseudogene does not produce a functional protein and thus is not a therapeutic target. In contrast, the functional "POTE ankyrin domain family member C" gene/protein (POTEC, ENSG00000183206) is expressed in some cancers and may participate in apoptosis and membrane interactions, but the pseudogene variant encoded by ENSG00000289133 lacks function[1][2][7]. Key clarification: - This entry, ENSG00000289133, is a **pseudogene** of POTEC and is not a protein-coding target. The therapeutically relevant target, when discussed, is encoded by the functional gene/protein (POTEC, ENSG00000183206), not this pseudogene[1][2][7]. - If you require druggable or target information, you should reference the functional gene/protein "POTE ankyrin domain family member C" (POTEC)[2][7].