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Target intelligence / Profile preview
POTE ankyrin domain family member D (POTED)
- Target
- POTED
- Molecular classification
- Other (ankyrin repeat domain-containing protein)
01
Overview
POTE ankyrin domain family member D (POTED) is a protein-coding gene belonging to the POTE gene family, which is characterized by ankyrin repeat domains and is predominantly expressed in reproductive tissues—including the prostate, ovary, testis, and placenta—and in certain cancers such as prostate cancer[1][2][6]. The protein may play a role in apoptosis, especially during spermatid development in the testis, and is classified as a cancer/testis antigen due to its tumor-associated tissue-restricted expression[5]. POTED does not have known drug interactions or established therapeutic targeting roles and is mainly of interest as a putative biomarker or antigen in the context of cancer[5].
- Other names
- ANKRD21A26B3POTEProtein POTEPOTE-21POTE21CT104.1ANKRD26-like family B member 3Ankyrin repeat domain-containing protein 21Prostate, ovary, testis-expressed protein, cancer/testis antigen family 104, member 1
02
Biological functions
Possibly involved in apoptosiscancer/testis antigen activityexpression in gametogenesis-related tissues such as prostate, ovary, testis, and placenta
03
Disease associations
Cancer (notably prostate cancer)Developmental Dysplasia of the Hippossibly other reproductive system diseases
04
Biomarkers
Potential cancer/testis antigen (biomarker for some cancers such as prostate cancer)not established as a widely adopted clinical biomarker
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