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PPARGC1A Antisense RNA 1 (PPARGC1A-AS1) is a human long non-coding RNA gene residing on the opposite strand of the PPARGC1A locus. It is classified as an lncRNA and designated AC092834.1 in transcriptomic databases. The specific regulatory function, disease association, and translational relevance of PPARGC1A-AS1 remain unknown as of 2024. It is not considered a canonical drug target or biomarker, and there are no approved drugs interacting with this gene. PPARGC1A-AS1 should not be confused with PPARGC1A, which encodes the protein Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), a master regulator of mitochondrial biogenesis and energy metabolism.
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