PPP1R12A antisense RNA 2 (PPP1R12A-AS2)

PPP1R12A antisense RNA 2 (PPP1R12A-AS2) is a long non-coding RNA (lncRNA) gene located in the human genome. It is transcribed as an antisense transcript in relation to the PPP1R12A (protein phosphatase 1 regulatory subunit 12A) protein-coding gene. To date, there is limited evidence for protein-coding potential or direct biological or pathological relevance for PPP1R12A-AS2. Most described functions for antisense RNAs like PPP1R12A-AS2 include roles in *regulation of their associated sense gene's expression* through mechanisms such as chromatin modification, transcriptional interference, RNA duplex formation, or mRNA stability, but there are no well-characterized or clinically validated functions or disease associations reported for PPP1R12A-AS2 itself[1]. There is also no evidence that PPP1R12A-AS2 is considered a therapeutic target, interacts with drugs, or serves as a biomarker based on currently available genome databases and literature[1]. **Note:** - This entry is distinct from the protein-coding gene PPP1R12A, which encodes a regulatory subunit for myosin phosphatase with established roles in signaling and disease. - PPP1R12A-AS2 (an RNA gene) should not be confused with PPP1R12A (a protein-coding gene)[1][3]. - There are no reports of interacting drugs, clinical biomarkers, or therapeutic mechanisms of action for PPP1R12A-AS2 at this time[1].

Other names

PPP1R12A-AS2PPP1R12A Antisense RNA 2