Target intelligence / Profile preview

PPP2R1A antisense RNA 1 (PPP2R1A-AS1)

Target
PPP2R1A-AS1
Molecular classification
Other, antisense long non-coding RNA, lncRNA
01

Overview

PPP2R1A antisense RNA 1 (PPP2R1A-AS1) is an antisense long non-coding RNA located opposite the PPP2R1A gene locus. While other antisense lncRNAs can regulate the transcription, stability, or translation of their corresponding sense genes, there is no published evidence on the specific biological activity, disease association, or druggability of PPP2R1A-AS1[6]. Most functional and therapeutic research focuses on the protein-coding PPP2R1A gene, which encodes a major scaffold subunit of protein phosphatase 2A (PP2A), a critical regulator of cell signaling and a recognized therapeutic target in oncology and neurodevelopmental diseases[1][3][4].

Other names
PPP2R1A-AS1
02

Biological functions

Potentially regulates PPP2R1A gene expression.

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