PRAC2 small nuclear protein (PRAC2)

PRAC2 small nuclear protein (PRAC2) is a gene highly expressed in the prostate, rectum, colon, and testis; minimal expression is seen in placenta and leukocytes[1][3][6]. The gene is annotated as potentially encoding either a small nuclear protein or a non-coding RNA; alternative splicing results in multiple transcript variants[3][6]. PRAC2 is part of a group of genes with tissue-enhanced or tissue-restricted expression, but its molecular function remains unclear—it may have roles in cell biology or tissue development, particularly in the prostate[4][1]. There is weak evidence suggesting PRAC2 might be implicated in cancer biology, most notably prostate cancer, but no definitive proof exists for a direct role in disease pathogenesis or as a therapeutic target[4][5]. PRAC2 is not classified as a receptor, enzyme, transporter, or transcription factor, and there are no approved drugs or well-described mechanisms of action, biomarker utility, or safety concerns linked to its modulation[3][6].

Other names

PRAC2Protein PRAC2C17orf93HOXB-AS5HOXB13-AS1NCRNA00253Prostate, rectum and colon expressed gene protein 2Small nuclear protein PRAC2HOXB cluster antisense RNA 5Putative protein PRCA2Chromosome 17 open reading frame 93HOXBAS5